Scientific Papers

2026

The following researches were conducted in 2026.

Safety assessment of SIRTMAX®, a standardized Kaempferia parviflora rhizome extract: genotoxicity and oral toxicity studies

【2026】

Haruka Oshikiri 1, Yukiko Kobayashi 1, Kwang-Soo Baek 2, Kunhee Park 2 and Jinwei Yang 1

 

  1. TOKIWA PHYTOCHEMICAL CO., LTD.
  2. Daehan Chemtech Co., Ltd.

 

Fundam. Toxicol. Sci.

2026, 13(5), 185-196

Safety assessment of Ilex paraguariensis leaf extract（MATESOL®）on mutagenicity, acute toxicity and human excessive intake

【2026】

Yukiko Kobayashi 1, Haruka Oshikiri 1, Tomoko Kuniyoshi 1, Tsuyoshi Takara 2, Jinwei Yang 1

  1. TOKIWA PHYTOCHEMICAL CO., LTD.
  2. Medical Corporation Seishinkai, Takara Clinic.

Jpn Pharmacol Ther

2026, 54(7), 487-99

Safety evaluation on excessive intake of Laurus nobilis leaf extract（LAURESH®） ―A randomized, double—blind, placebo—controlled, parallel—group comparison study―

【2026】

Yukiko Kobayashi 1, Kanami Ishikura 1, Haruka Oshikiri 1, Tsuyoshi Takara 2, Tomoko Kuniyoshi 1, Jinwei Yang 1

  1. TOKIWA PHYTOCHEMICAL CO., LTD.
  2. Medical Corporation Seishinkai, Takara Clinic.

Jpn Pharmacol Ther

2026, 54(7), 477-86

Mechanistic investigation of flavonoid-mediated inhibition of N-methyl-N-nitrosourea-induced mutagenicity via noncovalent DNA binding

【2026】

Chisato Matsuoka 1, Nao Takatama 1, Takuya Muraoka 1 and Keiko Inami 1

 

  1. Division of Pharmaceutical Organic Chemistry, Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University

 

Genes and Environment

(2026) 48:13

Kaempferia parviflora Rhizome Extract Improves Skeletal Muscle Glucose Homeostasis by Upregulating the GLUT4 Signaling Pathway In Vitro and In Vivo

【2026】

Seong-Hoo Park 1, Yeonhwa Lee 2, Soo-Jeung Park 3, Hyunyoung Choi 1, Jeongjin Park 2,4, Jinhak Kim 5,Kwang-Soo Baek 5, Kun Hee Park 5 and Woojin Jun 2,4

 

  1. Research Institute of Medical Nutrition, Kyung Hee University
  2. Division of Food and Nutrition, Chonnam National University
  3. Department of Culinary and Nutrition, Woosong University
  4. Research Institute for Human Ecology, Chonnam National University
  5. R&D Division, Daehan Chemtech Co., Ltd.

 

Pharmaceuticals

2026, 19, 754

NMR Characterization of Natural and Synthetic Anthocyanidins: Establishing a Foundation for Designing Functional O-Methylated Analogs

【2026】

Shunsei Shiozawa, Yukiko Kobayashi, Tadatoshi Yamashita, Jinwei Yang

 

Tokiwa Phytochemical Co., Ltd.

 

Natural product communications

Volume 21, Issue 4, April 2026