Safety assessment of Ilex paraguariensis leaf extract（MATESOL^®）on mutagenicity, acute toxicity and human excessive intake

Yukiko Kobayashi 1, Haruka Oshikiri 1, Tomoko Kyniyoshi 1, Tsuyoshi Takara 2, Jinwei Yang 1

1. TOKIWA PHYTOCHEMICAL CO., LTD.
2. Medical Corporation Seishinkai, Takara Clinic.