Research & Development

Composition for improving unidentified complaints, depression, impaired concentration, decreased motivation for socialization and daily activities, autonomic nervous system disorders, pain, control and poor sleep quality associated with menstruation

JP 7498993

2024-06-12

2023

Ilex paraguariensis A.St.-Hil. improves lipid metabolism in high-fat diet-fed obese rats and suppresses intracellular lipid accumulation in 3T3-L1 adipocytes via the AMPK-dependent and insulin signaling pathways

【2024】 Maya Kudo1*, Ming Gao1,2, Misa Hayashi1, Yukiko Kobayashi3, Jinwei Yang3 and Tonghua Liu4 School of Pharmacy and Pharmaceutical Science, Mukogawa Women’s University Institute for Bioscience, Mukogawa Women’s University Tokiwa Phytochemical Co., Ltd. Key Laboratory of Health Cultivation...

2024-01-23

Patent

COMPOSITION AND METHOD FOR IMPROVING QUANTITY OF TEAR FLUID, COMPOSITION, TREATING CONSTIPATION AND IMPROVING SKIN QUALITY

JP 7412743

2024-01-22

2023

Effect of Apocynum venetum Leaf Extract (VENETRON®) on Unidentified Complaints Relating Menstruation in Healthy Female Subjects－A Randomized, Double-blind, Placebo-controlled Parallel-group Comparison Study－

【2023】 Tomoko Kuniyoshi1), Yukiko Kobayashi1), Jinwei Yang1), Naoko Suzuki2), Tsuyoshi Takara3) TOKIWA PHYTOCHEMICAL CO., LTD. ORTHOMEDICO Inc. Medical Corporation Seishinkai, Takara Clinic. Jpn Pharmacol Ther 51(11), 1685-96 (2023)

2023-11-16

Patent

Antibacterial agent against periodontal disease-associated bacterium and dental caries-associated bacterium, composition for periodontal disease prophylaxis and treatment, composition for cavity prophylaxis and treatment, composition for gum improvement, composition for gum ridge improvement, composition for inhibiting plaque accumulation, composition for xerostomia improvement, composition for saliva improvement, composition for inhibiting bad breath, and composition for constipation improvement

JP 7349742

2023-09-29

2023

“Health Management Supplement® Rafuma & GABA” for Employees Subscription-based supplements as an employee benefit to support your valued employees’ mental and physical health.

【2023】 Ayumi Horie, Yukiko Kobayashi Tokiwa Phytochemical Co., Ltd. FOOD STYLE 2127(9) 82-85 (2023)

2023-09-05

2023

Quantitative determination method of Aconitum monoester alkaloids using relative molar sensitivity (RMS) for the assay in the Japanese Pharmacopoeia

【2023】 Nahoko Uchiyama,a*) Junko Hosoe,a) Kyoko Ishizuki,a) Ryoko Arai,a) Naoki Sugimoto,a) Azusa Suzuki,b) Ryuji Asano,b) Yasushi Igarashi,b) Toru Miura,c) Yasuhiro Muto,c) Takako Suematsu,d) Takanori Komatsu,d) Taro Higano,e) Takun Furukawa,e) Norimoto Shimada,f) Yukihiro Goda a*) a) National Institute...

2023-08-18

2023

Antiobesity effect of Kaempferia parviflora accompanied by inhibition of lipogenesis and stimulation of lipolysis

【2023】 Seong-Hoo Park1, Jeongjin Park2, Minhee Lee1, Jinhak Kim3, Sangwon Eun3, Woojin Jun2, Ok-Kyung Kim2 and Jeongmin Lee1. １. Department of Medical Nutrition, Kyung Hee University, Yongin, Republic of Korea 2. Division of Food and Nutrition and Human Ecology...

2023-07-05

2023

Anti-Aging Activity of Kaempferia parviflora Extract (SIRTMAX®) and its Standardizing Constituent 3,5,7,3′,4′-pentamethoxyflavone (PURESIRTMAX®)

【2023】 Chin Piow Wong1, Koji Nagata2, Tsutomu Ishikawa1, Jinwei Yang1, Jin Tatsuzaki1 １．Tokiwa Phytochemical Co., Ltd. ２．Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo 2023 American Society of...

2023-06-27

2023

Safety studies of LAURESH® a standardized Laurus nobilis leaf extract

【2023】 Chin Piow Wong 1), Yukiko Kobayashi 1), Jinwei Yang 1) 1) Tokiwa Phytochemical Co., Ltd. Fundamental Toxicological Sciences (Fundam. Toxicol. Sci.) 10 (4) 143-156 (2023)

2023-06-23

Composition for improving unidentified complaints, depression, impaired concentration, decreased motivation for socialization and daily activities, autonomic nervous system disorders, pain, control and poor sleep quality associated with menstruation

Ilex paraguariensis A.St.-Hil. improves lipid metabolism in high-fat diet-fed obese rats and suppresses intracellular lipid accumulation in 3T3-L1 adipocytes via the AMPK-dependent and insulin signaling pathways

COMPOSITION AND METHOD FOR IMPROVING QUANTITY OF TEAR FLUID, COMPOSITION, TREATING CONSTIPATION AND IMPROVING SKIN QUALITY

Effect of Apocynum venetum Leaf Extract (VENETRON®) on Unidentified Complaints Relating Menstruation in Healthy Female Subjects－A Randomized, Double-blind, Placebo-controlled Parallel-group Comparison Study－

“Health Management Supplement® Rafuma & GABA” for Employees Subscription-based supplements as an employee benefit to support your valued employees’ mental and physical health.

Quantitative determination method of Aconitum monoester alkaloids using relative molar sensitivity (RMS) for the assay in the Japanese Pharmacopoeia

Antiobesity effect of Kaempferia parviflora accompanied by inhibition of lipogenesis and stimulation of lipolysis

Anti-Aging Activity of Kaempferia parviflora Extract (SIRTMAX®) and its Standardizing Constituent 3,5,7,3′,4′-pentamethoxyflavone (PURESIRTMAX®)

Safety studies of LAURESH® a standardized Laurus nobilis leaf extract

Company Information

Sustainability