Scientific Papers

Natural food‐derived antimicrobials against beer spoilage microorganisms

【2025】Chang Liu 1, Jiale Tang 1, Peng Lu 1, Satoka Takabayashi 1, Dai Yagaki 1, Kenta Tsutsumi 1, Suguru Okuda 1,2, Hideaki Itoh 1, Hidenori Matsukura 3, Saki Toyota 3, Masaki Shimokawa 3, Koji Suzuki 4, Koji Nagata 1,2,5 1 Department...

• 2026-04-08

Evaluation of in vitro and in vivo genotoxicity, acute oral toxicity, and subacute oral toxicity of Apocynum venetum leaf extract VENETRON®

【2025】 Yukiko Kobayashi, Haruka Oshikiri, Jinwei Yang   Tokiwa Phytochemical Co., Ltd.   Fundamental Toxicological Sciences Vol. 13, No. 1 , 5-17, 2026

• 2026-02-25

MATESOL®: A new anti-obesity ingredient made from yerba mate, the mysterious tea in South America

【2025】 Kanade Someno, Kanami Ishikura Tokiwa Phytochemical Co., Ltd. FOOD STYLE 2129(8) 56-58 (2025)

• 2025-08-04

A Randomized, Placebo-Controlled, Double-Blind Trial to Assess the Effects of Apocynum venetum L. (A. venetum) Venetron^® on Sleep and Stress in Those Expressing Feelings of Anxiety

【2025】   Kaitlyn P. White 1, Susan Hewlings 1,*, Corey Bryant 1, Megan Moseley 1, Christopher R. D’Adamo 2, Christopher S. Colwell 3, Jeff Chen 1 and Emily K. Pauli 1   Radicle Science, Inc. Department of Family and Community...

• 2025-06-20

Kaempferia Parviflora Extract Reduces Body Fat in Adults Who are Overweight: A 12-Week Randomized, Double-Blind, Placebo-Controlled Trial

【2025】   Hyun Kyung Sung 1, Jinhak Kim 2, Dongchan Oh 2, Sang Won Eun 2, Jin Tatsuzaki 3, Seon Mi Shin 4, Su Hyeon Jeong 4   1. Dongguk University Gyeongju 2. Daehan Chemtech Co., Ltd. 3. Tokiwa Phytochemical...

• 2025-06-04

Sleep-promoting effects and potential mechanisms of Apocynum venetum leaf extract (VENETRON®): Effects of acute and chronic treatment on the sleep wake profiles in mice

【2025】   Duhyeon Kim a, Gibeom Choi a, Seonghui Kim a, Jinhak Kim b, Dongchan Oh b, Tatsuzaki Jin c, Jinwei Yang c, and Suengmok Cho a*   a. Department of Food Science and Technology, Institute of Food Science, Pukyong...

• 2025-05-26

Anthocyanins as Potent Inhibitors of Pentosidine Synthesis: Antioxidant-Mediated Effects

【2024】 〇Mai Asakura1,2, Kazuya Toriumi1, Aya Nozaki3, Jinwei Yang3, Jin Tatsuzaki3, Kazuhiro Suzuki1,4, Mitsuhiro Miyashita1,5, Masanari Itokawa1, Makoto Arai1,2 2. Graduate School of Medical and Dental Sciences, Institute of Science Tokyo 3. Tokiwa Phytochemical Co., LTD. 4. Department of Community...

• 2024-11-19

Reduction Effect of Ilex paraguariensis Leaf Extract (MATESOL®) on Abdominal Fat Area in Healthy Subjects ―A Randomized, Double-blind, Placebo-controlled Parallel-group Comparison Study―

【2024】   Tomoko Kuniyoshi1, Haruka Oshikiri1, Yukiko Kobayashi1, Toyotada Ashino2, Ikuo Fukuhara3, Jinwei Yang1*   Tokiwa Phytochemical Co., Ltd. New Drug Research Center, Inc. Fukuhara Clinic   Jpn Pharmacol Ther 52(9), 1067-1076(2024)  

• 2024-10-01

Effects of Laurus nobilis Leaf Extract (LAURESH®) on Oral and Gut Microbiota Diversity in Mice

【2024】   Tetsuro Morikawa1, Durga Paudel2, Osamu Uehara3, Dedy Ariwansa1, Yukiko Kobayashi4, Jinwei Yang4, Koki Yoshida1 and Yoshihiro Abiko1   Division of Oral Medicine and Pathology, Department of Human Biology and Pathophysiology, School of Dentistry, Health Sciences University of Hokkaido,...

• 2024-07-01

Ilex paraguariensis A.St.-Hil. improves lipid metabolism in high-fat diet-fed obese rats and suppresses intracellular lipid accumulation in 3T3-L1 adipocytes via the AMPK-dependent and insulin signaling pathways

【2024】   Maya Kudo1*, Ming Gao1,2, Misa Hayashi1, Yukiko Kobayashi3, Jinwei Yang3 and Tonghua Liu4   School of Pharmacy and Pharmaceutical Science, Mukogawa Women’s University Institute for Bioscience, Mukogawa Women’s University Tokiwa Phytochemical Co., Ltd. Key Laboratory of Health Cultivation...

• 2024-01-23