Scientific Papers

Effect of Apocynum venetum Leaf Extract (VENETRON®) on Unidentified Complaints Relating Menstruation in Healthy Female Subjects－A Randomized, Double-blind, Placebo-controlled Parallel-group Comparison Study－

【2023】   Tomoko Kuniyoshi1), Yukiko Kobayashi1), Jinwei Yang1), Naoko Suzuki2), Tsuyoshi Takara3)   TOKIWA PHYTOCHEMICAL CO., LTD. ORTHOMEDICO Inc. Medical Corporation Seishinkai, Takara Clinic.   Jpn Pharmacol Ther 51(11), 1685-96 (2023)

• 2023-11-16

“Health Management Supplement® Rafuma & GABA” for Employees Subscription-based supplements as an employee benefit to support your valued employees’ mental and physical health.

【2023】 Ayumi Horie, Yukiko Kobayashi Tokiwa Phytochemical Co., Ltd. FOOD STYLE 2127(9) 82-85 (2023)

• 2023-09-05

Quantitative determination method of Aconitum monoester alkaloids using relative molar sensitivity (RMS) for the assay in the Japanese Pharmacopoeia

【2023】     Nahoko Uchiyama,a*) Junko Hosoe,a) Kyoko Ishizuki,a) Ryoko Arai,a) Naoki Sugimoto,a) Azusa Suzuki,b) Ryuji Asano,b) Yasushi Igarashi,b) Toru Miura,c) Yasuhiro Muto,c) Takako Suematsu,d) Takanori Komatsu,d) Taro Higano,e) Takun Furukawa,e) Norimoto Shimada,f) Yukihiro Goda a*)   a) National Institute...

• 2023-08-18

Antiobesity effect of Kaempferia parviflora accompanied by inhibition of lipogenesis and stimulation of lipolysis

【2023】   Seong-Hoo Park1, Jeongjin Park2, Minhee Lee1, Jinhak Kim3, Sangwon Eun3, Woojin Jun2, Ok-Kyung Kim2 and Jeongmin Lee1.   １. Department of Medical Nutrition, Kyung Hee University, Yongin, Republic of Korea 2. Division of Food and Nutrition and Human Ecology...

• 2023-07-05

Anti-Aging Activity of Kaempferia parviflora Extract (SIRTMAX®) and its Standardizing Constituent 3,5,7,3′,4′-pentamethoxyflavone (PURESIRTMAX®)

【2023】     Chin Piow Wong1, Koji Nagata2, Tsutomu Ishikawa1, Jinwei Yang1, Jin Tatsuzaki1   １．Tokiwa Phytochemical Co., Ltd. ２．Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo    2023 American Society of...

• 2023-06-27

Safety studies of LAURESH® a standardized Laurus nobilis leaf extract

【2023】     Chin Piow Wong 1), Yukiko Kobayashi 1), Jinwei Yang 1)   1) Tokiwa Phytochemical Co., Ltd.    Fundamental Toxicological Sciences (Fundam. Toxicol. Sci.) 10 (4) 143-156 (2023)

• 2023-06-23

HPLC analysis of ammonium glycyrrhizate listed in the European, United States, and Japanese Pharmacopoeias under reported and modifed　conditions: revision of the peak assignment for 18α‑glycyrrhizin in the European and United States Pharmacopoeias

【2022】   Kazuaki Kamata1,3 · Jin Tatsuzaki1· Tsutomu Ishikawa1 · Ryoko Arai2· Takashi Hakamatsuka2,4 · Nahoko Uchiyama2   1) Tokiwa Phytochemical Co., Ltd2) National Institute of Health Sciences3) Present Address: Gunma University Center for Food Science and Wellness 4) Present Address:...

• 2023-03-02

Corosolic acid improves glucose and insulin responses in middle-aged men with impaired fasting glucose: A randomized, double-blinded, placebo-controlled crossover trial

【2022】     Masanobu Hibi1), Yuji Matsui2), Sachiko Niwa2), Sachiko Oishi1), Aya Yanagimoto1), Takahiro Ono3), Tohru Yamaguchi2)   1) Biological Science Research Laboratories, Kao Corporation2) Health & Wellness Products Research Laboratories, Kao Corporation3) Ueno-Asagao Clinic    Journal of Functional Foods ...

• 2022-11-29

Assessment of in vitro, in vivo, and Clinical Safety of SIRTMAX® a Standardized Kaempferia parviflora Rhizome Extract

【2022】     Chin Piow Wong 1), Yukiko Kobayashi 1), Jinwei Yang 1)   1) Tokiwa Phytochemical Co., Ltd.    Jpn Pharmacol Ther  50 (10) 1889-1899 (2022)

• 2022-11-01

Characterization and Utilization of Disulfide-Bonded SARS-CoV-2 Receptor Binding Domain of Spike Protein Synthesized by Wheat Germ Cell-Free Production System

【2022】     Yutaro Yamaoka1)2), Sundararaj Stanleyraj Jeremiah1), Rikako Funabashi1), Kei Miyakawa1), Takeshi Morita1), Yusaku Mihana1)2), Hideaki Kato3), Akihide Ryo1)   1) Department of Microbiology, Yokohama City University Graduate School of Medicine2) Life Science Laboratory, Technology and Development Division, Kanto Chemical Co.,...

• 2022-10-13