Scientific Papers

The effect of food containing Apocynum venetum leaf extract on daytime sleepiness, stress, in daily life, and concentration —A randomized, double—blind, placebo—controlled, crossover study—

【2022】   Kohei Fujiki1), Yuki Hirashima1), Takatoshi Ogami1), Akira Takano1), Tomoyasu Kamiya1), Kinya Takagaki1), Yoshitaka Iwama2)   1) Toyo Shinyaku Co., Ltd.2) Nihonbashi Cardiology Clinic   Jpn Pharmacol Ther　50 (4) 733-741 (2022)

• 2022-09-06

The Effects of Consuming a Tablet Supplement Containing Terminalia bellirica and Banaba Leaf Extracts on Postprandial Blood Triglycerides and Glucose in Healthy Japanese Subjects – A Randomized, Double-blind, Placebo-controlled, Crossover trial –

【2020】   Kageyama M 1), Tomobe H 1), Kobashi R 1), Nakashima N 1), Akiyoshi K 1), Omori R 1), Yamada A 1), Takahashi Y 2), Takara T 3).   1) DHC Corporation 2) ORTHOMEDICO Inc.3) Medical Corporation Seishinkai, Takara Clinic...

• 2022-09-05

Successful Commercialization of an Anti-Aging Ingredient Based on Advanced Research: Latest Advancement of SIRTMAX®( Kaempferia parviflora extract) in SIRT1 Activation and Clinical Study

【2022】 Jin Tatsuzaki Tokiwa Phytochemical Co., Ltd.  International Conference of the Modernization of Chinese Medicine & Health Products (ICMCM) 2022（HongKong） 11 August 2022 ～ 12 August 2022※Onsite & Online Hybrid

• 2022-08-17

”Oral health first” The base of health start from mouth. Oral care with tokiwa’s “LAURESH®”

【2022】 Ayumi Horie, Yukiko Kobayashi Tokiwa Phytochemical Co., Ltd. FOOD STYLE 2126(7) 58-60 (2022)

• 2022-07-26

Anti-skin Aging Activities of Sideritis scardica and 3 Flavonoids With an Uncommon 8-Hydroxyl Moiety

【2022】   Fumiaki Sato1), Chin Piow Wong2), Kaito Furuya1), Chikako Kuzu1), Ryousuke Kimura1), Tomoha Udo1), Haruno Honda2), Jinwei Yang2)    1) Laboratory of Analytical Pathophysiology, Hoshi University 2) Tokiwa Phytochemical Co., Ltd.   Natural Product Communications17(5) 1-10 (2022)

• 2022-05-09

Is 18α-Glycyrrhizin a real natural product? Improved preparation of 18α-Glycyrrhizin from 18β-Glycyrrhizin as a positive standard for HPLC analysis of licorice extracts

【2022】  

• 2022-01-28

The effect of ingesting of foods containing Laurus nobilis leaf extract（LAURESH^®） on oral environment in healthy subjects —A randomized, double—blind, placebo—controlled parallel—group comparison study—

【2021】 Tomoko Kuniyoshi1), Yukiko Kobayashi1), Haruno Honda1), Chin Piow Wong1), Toui Abe2), Jinwei Yang1), Masahiko Horiuchi3) 1) Tokiwa Phytochemical Co., Ltd.2) ORTHOMEDICO Inc.3) Medical Corporation Yuseikai, Horiuchi Dental Clinic Jpn Pharmacol Ther　49 (11) 1913-24 (2021)

• 2021-11-29

The functions of Kaempferia parciflora extract SIRTMAX^® and Kaempferia parciflora-derived polymethoxyflavonoid PURESIRTMAX^® through SIRT1 activation

【2021】   Haruno HONDA, Jinwei YANG    Tokiwa Phytochemical Co. Ltd.   Journal of Japanese Society for Medical Use of Functional FoodsVol.15 No.2 (2021)

• 2021-10-12

All-Trans Retinoic Acid Exhibits Antiviral Effect against SARS-CoV-2 by Inhibiting 3CLpro Activity

【2021】 Takeshi Morita 1, Kei Miyakawa 1, Sundararaj Stanleyraj Jeremiah 1, Yutaro Yamaoka 1,2, Mitsuru Sada 3, Tomoko Kuniyoshi 4, Jinwei Yang 4, Hirokazu Kimura 5, Akihide Ryo 1 1 Department of Microbiology, Yokohama City University Graduate School of Medicine2...

• 2021-09-10

The activation mechanism of longevity gene product SIRT1 by black turmeric polyphenol

【2021】   Mimin Zhang1 , Jin Tatsuzaki2 , Koji Nagata1   1 Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo2 Tokiwa Phytochemical Co. Ltd.   BIOSCIENCE & INDUSTRYVol.79 No.5 (2021)

• 2021-09-10