研究報告_2026

Safety assessment of Ilex paraguariensis leaf extract（MATESOL^®）on mutagenicity, acute toxicity and human excessive intake

【2026】

Yukiko Kobayashi 1, Haruka Oshikiri 1, Tomoko Kuniyoshi 1, Tsuyoshi Takara 2, Jinwei Yang 1

TOKIWA PHYTOCHEMICAL CO., LTD.
Medical Corporation Seishinkai, Takara Clinic.

Jpn Pharmacol Ther

2026, 54(7), 487-99

Safety evaluation on excessive intake of Laurus nobilis leaf extract（LAURESH^®） ―A randomized, double—blind, placebo—controlled, parallel—group comparison study―

【2026】

Yukiko Kobayashi 1, Kanami Ishikura 1, Haruka Oshikiri 1, Tsuyoshi Takara 2, Tomoko Kuniyoshi 1, Jinwei Yang 1

TOKIWA PHYTOCHEMICAL CO., LTD.
Medical Corporation Seishinkai, Takara Clinic.

Jpn Pharmacol Ther

2026, 54(7), 477-86

Kaempferia parviflora Rhizome Extract Improves Skeletal Muscle Glucose Homeostasis by Upregulating the GLUT4 Signaling Pathway In Vitro and In Vivo

【2026】

Seong-Hoo Park 1, Yeonhwa Lee 2, Soo-Jeung Park 3, Hyunyoung Choi 1, Jeongjin Park 2,4, Jinhak Kim 5,Kwang-Soo Baek 5, Kun Hee Park 5 and Woojin Jun 2,4

Research Institute of Medical Nutrition, Kyung Hee University
Division of Food and Nutrition, Chonnam National University
Department of Culinary and Nutrition, Woosong University
Research Institute for Human Ecology, Chonnam National University
R&D Division, Daehan Chemtech Co., Ltd.

Pharmaceuticals

2026, 19, 754

Mechanistic investigation of flavonoid-mediated inhibition of N-methyl-N-nitrosourea-induced mutagenicity via noncovalent DNA binding

【2026】

Chisato Matsuoka 1, Nao Takatama 1, Takuya Muraoka 1 and Keiko Inami 1

Division of Pharmaceutical Organic Chemistry, Faculty of Pharmaceutical Sciences, Sanyo-Onoda City University

Genes and Environment

(2026) 48:13

NMR Characterization of Natural and Synthetic Anthocyanidins: Establishing a Foundation for Designing Functional O-Methylated Analogs

【2026】

Shunsei Shiozawa, Yukiko Kobayashi, Tadatoshi Yamashita, Jinwei Yang

Tokiwa Phytochemical Co., Ltd.

Natural product communications

Volume 21, Issue 4, April 2026

研究報告

2026年度

Safety assessment of Ilex paraguariensis leaf extract（MATESOL®）on mutagenicity, acute toxicity and human excessive intake

Safety evaluation on excessive intake of Laurus nobilis leaf extract（LAURESH®） ―A randomized, double—blind, placebo—controlled, parallel—group comparison study―

Kaempferia parviflora Rhizome Extract Improves Skeletal Muscle Glucose Homeostasis by Upregulating the GLUT4 Signaling Pathway In Vitro and In Vivo

Mechanistic investigation of flavonoid-mediated inhibition of N-methyl-N-nitrosourea-induced mutagenicity via noncovalent DNA binding

NMR Characterization of Natural and Synthetic Anthocyanidins: Establishing a Foundation for Designing Functional O-Methylated Analogs

Safety assessment of Ilex paraguariensis leaf extract（MATESOL^®）on mutagenicity, acute toxicity and human excessive intake

Safety evaluation on excessive intake of Laurus nobilis leaf extract（LAURESH^®） ―A randomized, double—blind, placebo—controlled, parallel—group comparison study―